Best Bets for NCAA Basketball Picks Against the Spread for Wednesday, January 1

Published 1:21 am Wednesday, January 1, 2025

The UConn Huskies versus the DePaul Blue Demons is one of many strong options on Wednesday in college basketball play — suggested picks against the spread for 10 games are available in this article.

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Today’s NCAA Men’s Basketball Picks ATS

ATS Pick: DePaul +11.5 vs. UConn

Matchup: UConn Huskies at DePaul Blue Demons
Time: 2:00 PM ET
Date: January 1
Computer Projection: UConn by 2.5 points (Bet now on BetMGM)
Spread: UConn (-11.5)
TV Channel: CBS Sports Network
Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Rice +2.5 vs. Tulsa

Matchup: Rice Owls at Tulsa Golden Hurricane
Time: 3:00 PM ET
Date: January 1
Computer Projection: Rice by 2.1 points (Bet now on BetMGM)
Spread: Tulsa (-2.5)
TV Channel: ESPN+
Live Stream: Watch this game on ESPN+

ATS Pick: Valparaiso +4.5 vs. Missouri State

Matchup: Valparaiso Beacons at Missouri State Bears
Time: 8:00 PM ET
Date: January 1
Computer Projection: Valparaiso by 0.1 points (Bet now on BetMGM)
Spread: Missouri State (-4.5)
TV Channel: ESPN+
Live Stream: Watch this game on ESPN+

ATS Pick: Butler +1.5 vs. Villanova

Matchup: Villanova Wildcats at Butler Bulldogs
Time: 6:30 PM ET
Date: January 1
Computer Projection: Butler by 2.6 points (Bet now on BetMGM)
Spread: Villanova (-1.5)
TV Channel: Fox Sports 1
Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Purdue Fort Wayne +1.5 vs. Northern Kentucky

Matchup: Purdue Fort Wayne Mastodons at Northern Kentucky Norse
Time: 12:00 PM ET
Date: January 1
Computer Projection: Purdue Fort Wayne by 2.3 points (Bet now on BetMGM)
Spread: Northern Kentucky (-1.5)
TV Channel: ESPN+
Live Stream: Watch this game on ESPN+

Bet on this or any men’s college basketball matchup at BetMGM.

ATS Pick: Bradley -3.5 vs. Indiana State

Matchup: Bradley Braves at Indiana State Sycamores
Time: 7:00 PM ET
Date: January 1
Computer Projection: Bradley by 7.0 points (Bet now on BetMGM)
Spread: Bradley (-3.5)
TV Channel: ESPN+
Live Stream: Watch this game on ESPN+

ATS Pick: Stanford +10.5 vs. Clemson

Matchup: Stanford Cardinal at Clemson Tigers
Time: 4:00 PM ET
Date: January 1
Computer Projection: Clemson by 7.0 points (Bet now on BetMGM)
Spread: Clemson (-10.5)
TV Channel: ACC Network
Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: North Carolina +1.5 vs. Louisville

Matchup: North Carolina Tar Heels at Louisville Cardinals
Time: 6:00 PM ET
Date: January 1
Computer Projection: North Carolina by 1.1 points (Bet now on BetMGM)
Spread: Louisville (-1.5)
TV Channel: ACC Network
Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Mercer +2.5 vs. Chattanooga

Matchup: Chattanooga Mocs at Mercer Bears
Time: 3:00 PM ET
Date: January 1
Computer Projection: Mercer by 0.1 points (Bet now on BetMGM)
Spread: Chattanooga (-2.5)
TV Channel: ESPN+
Live Stream: Watch this game on ESPN+

ATS Pick: Northern Iowa -6.5 vs. Belmont

Matchup: Belmont Bruins at Northern Iowa Panthers
Time: 9:00 PM ET
Date: January 1
Computer Projection: Northern Iowa by 9.0 points (Bet now on BetMGM)
Spread: Northern Iowa (-6.5)
TV Channel: ESPN+
Live Stream: Watch this game on ESPN+

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