Gerald Henderson scored a career-high 25 points Saturday, leading second-ranked Duke to a 66-58 victory at Florida State.

The Blue Devils (14-1, 2-0 Atlantic Coast Conference) ran off the first nine points of the second half during a 41-11 run to build their largest lead of the game, 46-21 with 12:45 left.

Toney Douglas led Florida State (13-3, 0-1) with 18 points, but was just 7-of-23 from the floor as the Seminoles shot just 31 percent.

Duke led 19-14 at the half.

No. 6 Oklahoma 61, Kansas St. 53

MANHATTAN, Kan. (AP) — Blake Griffin had 29 points and 15 rebounds in a rare game against single coverage, helping Oklahoma open Big 12 Conference play with a win.

Oklahoma (15-1) was 9-7 and won just three road games in the Big 12 last season.

Denis Clemente led Kansas State (11-4) with 18 points and Fred Brown added 12.

No. 8 Michigan St. 75, Kansas 62

EAST LANSING, Mich. (AP) — Kalin Lucas continued his offensive surge, scoring 22 points to lead the eighth-ranked Spartans over the defending national champions.

Michigan State (13-2) has won nine straight since getting routed by North Carolina, 27 in a row at the Breslin Center over nearly two years and 39 consecutive against nonconference opponents at home since losing to Duke in 2003.

Sherron Collins and Cole Aldrich, the only current players who had an impact on last season’s national championship team, scored 25 and 14 points respectively for the Jayhawks (11-4) and reserve Tyrel Reed added 10 points.

Michigan State’s Raymar Morgan had 13 points and eight rebounds and Travis Walton scored 11.

No. 9 Georgetown 82, Providence 75

WASHINGTON (AP) — Austin Freeman scored 18 points, Greg Monroe nearly had a triple-double, and Georgetown held Providence scoreless for more than 6 minutes to rally for a victory that ended its two-game Big East losing streak.

Georgetown (11-3, 2-2) trailed by nine points in the first half, and allowed Providence (11-5, 3-1) to go ahead 44-40 on Brian McKenzie’s 3-pointer with 16:15 left.

No. 12 Clemson 63, North Carolina State 51

CLEMSON, S.C. (AP) — Trevor Booker scored 23 points and Clemson improved to 16-0.

The Tigers (2-0 Atlantic Coast Conference) are within a win of tying the school’s best start, accomplished in 1986-87 and matched two years ago.

No. 13 Notre Dame 88, Seton Hall 79

SOUTH BEND, Ind. (AP) — Luke Harangody scored 30 points to lead Notre Dame as the Irish tied a Big East record with their 20th consecutive league win at home.

The Irish (12-3, 3-1 Big East) have won 45 straight overall at home. The Pirates (9-7, 0-4) have lost four straight this season and six straight to the Irish.

Harangody made four of his first five shots then missed his next 10. He found his shooting touch in the final 10 minutes, though, making four of his final eight shots to become the first Notre Dame player to score at least 20 points in eight straight games since Kelly Tripucka accomplished the feat in 1980.

Eugene Harvey led the Pirates with 21 points, Robert Mitchell added 15 points and Jordan Theodore had 11.

Tory Jackson and Kyle McAlarney had 18 points each for the Irish. There were 14 ties and 14 lead changes in the game.